Reviewing Glyphosate Genotoxicity in Humans
نویسندگان
چکیده
منابع مشابه
Review of genotoxicity studies of glyphosate and glyphosate-based formulations.
An earlier review of the toxicity of glyphosate and the original Roundup™-branded formulation concluded that neither glyphosate nor the formulation poses a risk for the production of heritable/somatic mutations in humans. The present review of subsequent genotoxicity publications and regulatory studies of glyphosate and glyphosate-based formulations (GBFs) incorporates all of the findings into ...
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Somatic cell gene mutations arising in vivo in humans provide biomarkers for genotoxicity. Four assays, each measuring changes in a different "recorder" gene, are available for detecting mutations of the hemoglobin (Hb) and glycophorin A (gpa) genes in red blood cells and the hypoxanthine-guanine phosphoribosyltransferase (hprt) and HLA genes in T-lymphocytes. Mean adult background mutant frequ...
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Herbicides have been extensively used in agriculture but people have not concerned about its adverse effects on plants and animals. The aim of the present study is to analyze the detrimental effects of two herbicides in Fagopyrum esculentum Moench (Variety: VL-7). The root tips were treated with four concentrations viz. 50, 100, 150 and 200 ppm of glyphosate and atrazine at room temperature for...
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There is considerable controversy with regard to the genotoxicity of glyphosate, with some reports stating that this compound is non-toxic for fish, birds and mammals. In this work, we used the comet assay to examine the genotoxicity of glyphosate isopropylamine (0.7, 7, 70 and 700 μM) in human lymphocytes, erythrocytes of Oreochromis niloticus and staminal nuclei of Tradescantia (4430) in vitr...
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ژورنال
عنوان ژورنال: ISEE Conference Abstracts
سال: 2020
ISSN: 1078-0475
DOI: 10.1289/isee.2020.virtual.p-0788